Hardrock EPH-100 is a dietary supplement containing a mixture of active ingredients that allow effective weight reduction while maintaining well-being - anhydrous caffeine, Ephedra viridis extract, yohimbine, phenylethylamine, glucuronolactone, nettle root extract, L-phenylalanine and theophylline .
Caffeine - a compound from the methylxanthine group, one of the most popular stimulants. It acts antagonistically to adenosine receptors, thereby reducing fatigue, which in effect allows for longer and more effective performance of intellectual and physical activities. Centrally, it probably contributes to increased secretion of serotonin, and can also improve cholinergic and dopaminergic transmission. It has been found that it may also support lipolysis in adipose tissue cells by increasing the amount of intracellular cAMP (blocking the activity of the decomposing phosphodiesterase) and indirectly activating the "enzymatic lipolysis apparatus".
Extract from Ephedra viridis contains substances that affect the sympathetic component of the vegetative system. This results in increased production of thermal energy in muscle tissue, as well as the use of energy substrates (glucose and fatty acids) supplied from food or adipocytes. An additional effect of reducing the transport of glucose to adipose tissue prevents the storage of spare substances in it.
Yohimbine is an alkaloid obtained from an African tree called Johimba lekarska. Its action is based on the blocking of alpha2-adrenergic receptors, thereby abolishing the inhibition of noradrenaline secretion into the blood, which acts both lipolytically (peripherally) and supports the secretion of neurotransmitters (dopamine, serotonin), which along with noradrenaline and cortisol modulate the mood. This compound can also raise blood pressure and act aphrodisiac - by activating the sympathetic system supports erection, which can also be helpful during end-stage reduction, where the libido is significantly reduced.
Phenylethylamine works centrally (within the CNS), binds to TAAR1 receptors, thereby inhibiting the uptake of dopamine, serotonin and noradrenaline. The first of them are substances that are responsible for our positive mood, feeling pleasure. Noradrenaline belongs to catecholamines - hormones that help the release of energy substances from the adipose tissue by means of a molecular mechanism, and also by interacting with methylxanthines.
Glucuronolactone - a glucose metabolite that is formed in the liver. It can be converted to xylitol, glucaric acid and L-xylolysis. As a derivative of glucuronic acid, its detoxification effect is postulated - it binds to toxins, increases their solubility in water and allows excretion via the kidneys.
The nettle root extract is rich in many chemical compounds and has a wide spectrum of activity. Stinging nettle is a source of organic acids, flavonoids, tannins and many other substances, however, sterols - beta-sitosterol deserve special mention. The main actions are postulated that the active ingredients may contribute to an increase in the concentration of free testosterone in the blood (due to the inhibition of alpha-5-reductase and aromatase, as well as reducing the production of SHGB transporting testosterone). They can also inhibit the development of prostate cancer and also have anti-inflammatory effects.
L-Phenylalanine is a compound belonging to the group of exogenous amino acids, involved in many important processes in the body. It is the starting substrate in the reactions of formation of catecholamines as well as phenylethylamine - a compound already contained in this supplement, thus increasing its effect.
Theophylline is another methylxanthine that has a caffeine-like effect and is compatible with catecholamines. In addition, however, it can increase blood pressure, while improving the blood flow through the kidneys, and also facilitates breathing, relaxing the smooth muscle of the bronchi. During physical exercise, proper ventilation is important to avoid taking oxygen debt, and the kidneys receive a reduced amount of blood - theophylline can be extremely helpful here.
1 capsule twice a day.