Haya Glycine 100 caps - regeneration of the nervous system
Haya Glycine is a dietary supplement providing pure glycine - the simplest amino acid, which has many fundamental functions in the human body. Glycine has a neuroprotective function, which means that it protects nerve cells from oxidative stress and inflammation. It inhibits excessive activity of glutamate - an excitotoxic neurotransmitter, the excess of which can lead to neuronal damage. What's more, it has a very good effect on sleep, improves regeneration and helps improve well-being.
The benefits of glycine include:
- Support for the nervous system
- Falling asleep faster
- Improving cognitive functions
- Improving mood
What is glycine?
Glycine is the simplest endogenous amino acid, which means that the human body is able to synthesize it on its own. Despite its simple chemical structure (it has only one hydrogen atom as a side chain, hence it is not chiral), glycine plays a fundamental role in numerous metabolic and physiological processes. It is a component of proteins, including collagen, which is key for connective tissue, acts as a neurotransmitter in the central nervous system, and participates in the synthesis of hemoglobin, creatine, glutathione and nucleic acids.
Key Metabolic Functions of Glycine
Glycine is involved in many critical metabolic pathways:
- Protein Synthesis: It is a component of many proteins, making up about one-third of all the amino acids in collagen, the main protein in connective tissue, skin, bones, and cartilage.
- Creatine Synthesis: Together with arginine and methionine, glycine is a precursor to creatine, a compound that plays a key role in providing energy to cells muscle during intense exercise.
- Glutathione synthesis: Glycine is one of three amino acids (along with cysteine and glutamic acid) that make up glutathione – the main endogenous antioxidant, essential for detoxification and protection of cells from oxidative stress.
- Purine and pyrimidine synthesis: Glycine is a substrate in the synthesis of purine and pyrimidine bases, key components of DNA and RNA.
- Bile acid conjugation: In the liver, glycine is used to conjugate bile acids to form bile salts, which are essential for digesting and absorbing fats.
How does glycine work?
Improve Sleep Quality
One of the most well-studied benefits of glycine supplementation is its positive effect on sleep quality. Glycine acts as an inhibitory neurotransmitter in the central nervous system, particularly in the spinal cord and brainstem. It interacts with glycerol receptors to increase the permeability of the cell membrane to chloride ions, which leads to hyperpolarization of neurons and reduced excitability. In the context of sleep, glycine can affect thermoregulation by lowering body temperature, which is a signal that promotes sleep.
Supporting Skin, Joint and Connective Tissue Health: Role in Collagen Synthesis
Glycine is the most abundant amino acid in collagen, making up about one-third of its structure. Collagen is the main structural protein in skin, bones, cartilage, tendons and ligaments. Its synthesis requires significant amounts of glycine. As we age or as a result of factors such as oxidative stress, collagen production can decline, leading to loss of skin elasticity, weakened bones and joint problems.
Role in Detoxification Processes: Glutathione Synthesis
Glutathione is a key antioxidant and plays a central role in the body's detoxification systems, including neutralizing free radicals, metabolizing xenobiotics (substances foreign to the body), and removingtion of heavy metals. Glutathione synthesis requires the availability of glycine, cysteine, and glutamic acid.
Effects on Metabolism and Blood Sugar Regulation Potential
Glycine may play a role in regulating blood glucose levels. Studies suggest that it may stimulate the secretion of incretins (gut hormones such as GLP-1), which increase insulin secretion in response to a meal, and may also directly affect pancreatic beta cells. Additionally, glycine may modulate the function of NMDA receptors, which are involved in glucose metabolism.
Glycine Dosage
1 serving, 3 capsules before bed.