Freedom Formulations FF Myosarm YK-11 90 caps myostatin blocker
Freedom Formulations Myosarm is structurally similar to DHT, commonly classified as SARMs, compounds that selectively activate androgen receptors. In order to activate androgen receptors without causing the adverse effects associated with excessive amounts of androgens, a newly created group of compounds called Selective Androgen Receptor Modulators (SARMs) has been identified.\ The term SARMs refers to a group of substances, both steroidal and non-steroidal, which act as ligands of androgen receptors (ARs). ) attached to hormone-binding domains (LBD), influence their functions.
How do SARMs work?
Ideal SARMs are characterized by high strength of interaction with AR, usually greater than endogenous androgens, and tissue specificity, thanks to which they are able to activate AR in selected areas of the body, including muscles, bones or nervous system, bypassing, for example, the prostate, leading to the desired effects. . As a rule, they are not a substrate for 5a-reductase and aromatase, and thus are not subject to transformation into DHT and estrogens, and therefore are not associated with the negative consequences of the activity of the mentioned hormones. (17α,20E)-17,20-[(1-methoxyethylidene)bis-(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl.
Freedom Formulations FF Myosarm YK-11 is:
- Myostatin blocker,
- Supports the construction of muscle mass,
- Helps break the stagnation
- Supports building strength,
- Improves insulin sensitivity.
How does the myostatin blocker YK-11 work?
Yk 11 has been classified as one of the most effective SARMs that strongly activate anabolic processes in specific areas of the body. As a ligand showing a certain tissue specificity and high affinity for AR (greater than in the case of testosterone or DHT), it is able to strongly bind selected androgen receptors. Nevertheless, its actions do not fully coincide with those assigned to SARMs, as evidenced by the inability to induce N / C interactions, and thus only partial agonism of these receptors.
YK-11, apart from its inability to fully activate androgen receptors, is able to increase the level of major myogenic regulatory factors (MRFs), especially MyoD, Myf5 and myogenin, in a greater way than DHT does.
YK-11 allows the myogenesis process to take place mainly by increasing the concentration of follistatin (FST), which reduces the activity of myostatin, a protein that limits the process of muscle growth beyond the naturally programmed size. Apart from the influence of (17α, 20E) -17.20 - [(1-methoxyethylidene) bis- (oxy)] - 3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester on androgen receptors and activation , or inactivation of certain proteins, the influence on the proportion of hormones in the body and its possible effect on the liver is unknown so far. YK-11 is an extremely strong anabolic product which, mainly by increasing folistin and MRFs and blocking myostatin, is able to increase the synthesis of new muscle fibers. By supporting the development of muscle mass, with the simultaneous loss of unnecessary fat, it leads to the exposure of an extremely muscular and lean body.
Dosage of YK11 miostatin inhibitor MyoSarm:
1-3 capsules a day.