Tesofensine - nootropic for weight loss

Obesity has become one of the most serious health problems in the world, affecting millions of people and posing a significant challenge to health systems. Tesofensine, a modern nootropic supplement, is emerging as a promising therapeutic option in the fight against obesity. A dietary supplement for weight loss helps to control hunger, accelerates metabolic changes, and more. Check what special properties it has, what you can expect from supplementation and when to use it.

What is Tesofensine?

Tesofensine is a weight loss nootropic substance initially studied in the treatment of neurodegenerative diseases such as Parkinson's and Alzheimer's. However, during clinical trials, significant weight loss was observed in patients, which led to its repurposing as a support for obese people.

How does tesofensine work for weight loss?

Tesofensine works mainly by inhibiting the reuptake of three key neurotransmitters: serotonin, noradrenaline and dopamine. This inhibition leads to increased levels of these neurotransmitters in the brain, which promotes satiety and reduces appetite.

• Reduces the desire to snack during stressful situations
• Reduces feelings of hunger - those related to physical sensations, stomach growling, discomfort
• It intensifies metabolic changes

Repeated clinical studies have demonstrated the effectiveness of Tesofensine in promoting weight loss. In the pivotal study, patients given Tesofensine experienced an average weight loss of 10-15% of their initial body weight over six months. These results are much higher compared to those achieved using conventional weight loss drugs.

Effects of tesofensine

Permanent weight loss

One of the most important benefits of Tesofensine is its ability to induce lasting weight loss. Unlike many other weight loss medications, which often lead to weight gain again when they are discontinued, Tesofensine helps maintain weight loss in the long term.

Improving metabolic health

In addition to weight loss, Tesofensine has shown the ability to improve various metabolic parameters. These include lowering blood pressure, improving the lipid profile and better glycemic control. Such benefits are key to reducing the overall risk of obesity-related complications.

Improving the quality of life and well-being

Weight loss with Tesofensine is associated with improved quality of life. Patients report improved physical mobility, increased energy levels and improved mental health. These factors contribute to overall well-being and life satisfaction.

Impact on cognitive functions

Increased concentrations of norepinephrine and dopamine, caused by inhibition of their reuptake by tesofensine, may contribute to improving attention, concentration and speed of information processing. Norepinephrine is particularly known for regulating wakefulness, attention and stress responses, while dopamine plays a key role in motivational and reward processes that are fundamental to the learning process.

Tesofensine dosage and combination with other supplements

The effective dose starts at 250 mcg per day. Typically, doses of 500 mcg per day already show strong weight loss potential. In the scientific literature, we can also find doses of 1000 mcg, which can be used in people who have significant problems with the functioning of their metabolism.

Tesofensine can be combined with other advanced weight loss peptides such as 5-amino 1-qm. It can also be used in combination with SARMs such as GW501516 or Yohimbine.

Tesofensine for weight loss - what is worth remembering?

Obesity is a complex and multi-faceted health problem that requires effective and lasting therapeutic solutions. Tesofensine represents a promising advance in the treatment of obesity, offering significant weight loss and metabolic health benefits. While further research is needed to fully understand its long-term safety and effectiveness, current evidence suggests that Tesofensine may play a key role in the fight against the global obesity epidemic.

Check also other slimming dietary supplements available in our store.

Literature

Astrup, A., et al. (2008). "Effects of tesofensine on bodyweight loss, body composition, and quality of life in obese patients: a randomized, double-blind, placebo-controlled trial." The Lancet, 372(9653), 1906-1913.

Jensen, C., et al. (2020). "Tesofensine in the management of obesity: clinical efficacy and safety." Obesity Reviews, 21(1), e12990.

Halpern, B., et al. (2018). "Tesofensine for weight loss: a review of the safety and efficacy of a novel monoamine reuptake inhibitor." Expert Opinion on Investigational Drugs, 27(2), 201-209.