Now Foods Cayenne is a dietary supplement containing the extract of Pepper fruit (Capsicum frutescens), the so-called Cayenne pepper, which is one of the best natural remedies used for weight loss, and modern scientific research indicates that it has anti-cancer properties and may support the cardiovascular system.
The main active ingredient of Capsicum frutescens is capsaicin, which is famous for its sharp taste. This organic chemical compound has analgesic, antioxidant, antibacterial, antihypertensive effect and, by affecting thermoregulation and fat metabolism, helps to reduce body fat. The latest reports also speak of its gastroprotective and anti-cancer properties.
Recent studies have shown that the mechanism of action of capsaicin is mainly based on the effect of TRPV1 pain receptors, which are often referred to as "capsaicin". They are located in the membranes of the nerve cells of the peripheral nervous system, and in response to a physical stimulus they cause pain sensations. The analgesic effect of capsaicin results from the fact that prolonged stimulation of these receptors causes their inactivation and ceases to be stimulated.
The effect of capsaicin on body temperature depends on the time that has elapsed since admission (sudden or late), the frequency of admission (one-time or cyclical), the dose, and TRPV1 receptor activity. Regular intake of capsaicin causes inactivation of the TRPV1 receptor and increases body temperature. Capsaicin also causes a change in the activity of calcium transporters in muscles, which leads to increased thermogenesis. The ATP-dependent calcium conveyor is a protein that transports calcium ions from the cytoplasm to the endoplasmic reticulum of muscle cells, which consumes energy resulting from the breakdown of high-energy bonds contained in ATP. Capsaicin causes this transporter to stop transferring calcium ions, but it still breaks down ATP and the energy is dissipated as heat.
Studies conducted on humans confirm the slimming effect of capsaicin. During its regular intake, there are changes in protein concentrations associated with thermogenesis and fat metabolism. It slows down the transcription of protein genes that stimulate the accumulation of adipose tissue and stimulates the transcription of protein genes associated with the thermogenesis process. In addition, it increases heat generation by enhancing the secretion of adrenaline and noradrenaline. It also affects the transcription of genes responsible for the production of enzymes that catalyze fat reduction reactions. In addition, capsaicin reduces the feeling of appetite. All these properties contribute to facilitating the reduction of body fat and weight loss.
1 capsule 2-3 times a day