Rich Piana's FULL AS FUCK is a pre-workout supplement, designed for all those who want to get the maximum "muscle pump" effect when training in the gym.
FULL AS FUCK includes, among others:
Agmatine Sulfate - is one of the newest and most exciting nutritional supplements with many physiological benefits, including as a pre-workout agent to support overall athletic performance. Agmatine sulphate shows various biochemical and physiological functions in the body, influences the synthesis of nitric oxide (NO), supports cardiovascular, neuromodulating and neurotransmitter (nootropic) functions. A properly selected dose of agmatine effectively increases the secretion of nitric oxide in the human body, which translates into a strong muscle pump feeling during training. The expansion of blood vessels supports the supply of blood and nutrients to the working muscles, which significantly accelerates the regeneration process and building new muscle fibers.
L-Citrulina - a non-protein amino acid, ornithine derivative, precursor of arginine and nitric oxide (NO) formed therefrom. It is an essential element of the urea cycle, the only effective way to remove toxic ammonia from the body. By increasing the production of nitric oxide, it helps relaxation of blood vessels and improves blood circulation, translating into better oxygenation and nutrition of cells. By improving endothelial nitric oxide synthesis and increasing reverse cholesterol transport (RCT), it has anti-atherosclerotic effects that prolong cardiovascular health. Nitric oxide formed from it enables proper functioning of the nervous system. Citrulline enhances the lipolysis process and inhibits the glyceroneogenesis process, increases the availability of energy substrates. In addition, independent of the action of insulin, it intensifies the anabolic processes of proteins.
L-Taurine - showing high structural similarity to GABA, under certain conditions is able to affect its assigned receptors. By limiting the production of serotonin, it counteracts the feeling of lethargy. By counteracting uncontrolled oxidation processes, it counteracts inflammation and supports the preservation of good health of the cardiovascular system. By inhibiting the influx of calcium through calcium channels dependent on the L-, N- and P / Q membrane potential, interfering with the release of toxic amounts of cytochrome C, limiting oxidative stress and preventing the activation of glutamate-induced chaplains, reduces the destruction of the nervous system. By reducing oxidative stress, restoring enzyme activity in glucose metabolism and improving insulin sensitivity, it supports the proper functioning of the carbohydrate and insulin metabolism. By regulating the concentration of intracellular calcium, the correctness of tension and the correctness of muscle contraction influence. Supporting the release of insulin and somatotropin and being a significant source of nitrogen, it improves the efficiency of muscle structure synthesis. By stabilizing the membranes, reducing the effectiveness of the adrenocorticotropic hormone (ACTH) and limiting the secretion of cortisol, it prevents the degradation of muscle tissue.
Glycerol Monostearate - a naturally occurring compound in our body. Its main function is to regulate the level of fluids in tissues and blood. The increased supply of glycerol results in an increase in the amount of water in our body, until the excess is removed by the kidneys. The benefits we derive from this phenomenon are: improved absorption of compounds taken together with glycerol, faster delivery of nutrients to cells, more anabolic environment, more visible use (associated with the movement of water from space, between muscle cells, into the blood) and more noticeable " pump effect "during trainings.
Beet root extract - due to the high content of betalain and by stimulation of Nrf2 activating the synthesis of endogenous antioxidant enzymes, it has a strong antioxidant effect, protecting the body's structures against free radicals, reactive oxygen species, and excessive iron aggression. It strongly counteracts lipid peroxidation. By inhibiting the nuclear transcription factor NF kappa B (NF-kB) and reducing the expression of cyclooxygenases 1 and 2, prostaglandins F2 and E2, lipoxygenase and proinflammatory cytokines TNF-α and IL-6, have anti-inflammatory and analgesic effects. By lowering the level of apoptosis markers: caspase-3, Bax and Bcl-2, it has anti-apoptotic properties. As a rich source of nitrates, transformed with the participation of the oral microflora into nitrites, which are then absorbed into the body are converted by means of appropriate nitric oxide (NO) reductases, support vasodilatation and proper functioning of the cardiovascular system. Supporting blood circulation in the brain supports its functioning.
L-Norvaline - a biologically active enantiomer of non-proteinaceous α-amino acid - norvaline. It is a non-selective inhibitor of arginase, an enzyme that breaks down arginine into ornithine and urea. By inhibiting the activity of arginase, it increases the availability of endogenous arginine for endothelial NO synthase (eNOS). It promotes its conversion to citrulline and nitric oxide (NO), an important vasoprotective agent, which by regulating the endothelial tone, affects: improvement of blood circulation in the bloodstream, inhibition of platelet aggregation, inhibition of leukocyte adhesion to the endothelium, oxygenation of cells and their detoxification . In addition, L-norvaline primarily reduces TNF-induced endothelium by inhibiting S6K1 kinase. L-norvaline has antiatherosclerotic activity.
1 serving 30 minutes before training.