Thermadex Black is a product aimed at reducing body fat. The success of Thermadex Black is based not on quantity, but on quality, which is the selection of only proven substances that allow quick burning of unnecessary body fat, while maintaining a good mood. Used during the daytime, as well as after training, it long-termes thermogenesis and intensifies lipolysis, allowing continuous burning of unnecessary fat tissue.
Thermadex Black consists of:
Caffeine - also known as 1,3,7-trimethylxanthine, a purine alkaloid of vegetable origin, most often identified with coffee seeds, evergreen trees and shrubs from the Marzena family, whose plantations are located in Africa, South America and Asia. Among the many properties of caffeine, the most noticeable is the stimulating effect, caused by selective antagonism of the adenosine A1 and A2A receptors leading to an increase in the amount of some neurotransmitters, including: acetylcholine, noradrenaline and dopamine. Caffeine, by inhibiting phosphodiesterase (PDE) activity, increases the concentration of cyclic AMP (cAMP), a compound important for maintaining full fitness and clarity of thinking. An additional feature of cAMP is the acceleration of degradation processes of glycogen and adipose tissue, supporting slimming and increasing the availability of energy substrates necessary to perform the training. The most important property of caffeine from the perspective of loss of superfluous fat tissue is the induction of internal depolarization of the mitochondrial membrane and increasing the amount of UCP - decoupling proteins intensifying thermogenesis and supporting the burning of fats and carbohydrates.
Theophylline - in other words 1,3-dimethylxanthine, a purine alkaloid found mainly in Theobroma cacao and leaves of Camellia sinensis. Its properties are primarily due to its phosphodiesterase (PDE) inhibiting activity, thereby reducing the degradation of cyclic adenosine-3 ', 5'-monophosphate (cAMP). By raising the level of cAMP and sensitizing beta receptors by increasing the effect of beta-agonists, it promotes chronotropic effects (influence on the frequency of myocardial contractions) and inotropic (impact on the strength of heart contraction), thus improving the functioning of the cardiovascular system. By expanding the smooth muscles and blood vessels of the lungs and relieving inflammation associated with the activity of neutrophils in the airways, it supports the work of the respiratory system. By increasing the concentration of cAMP enhances the process of disintegration and oxidation of adipose tissue. As a prostaglandin antagonist, it limits the extent of inflammation.
Bitter orange extract - bitter orange extract (Citrus aurantium), an evergreen tree of tropical and subtropical climate originating from Southeast Asia. It has antioxidant, analgesic, antibacterial, antidiabetic effects, improves renal parameters. The standardization of the extract under the account of synephrine transfers the priority of its action towards supporting the slimming process. Synephrine is a protoalkaloid with antioxidant, lipolytic and thermogenic properties, which primarily exerts its action by activating β-3 adrenergic receptors. Increasing the phosphorylation of AMPK leads to the translocation of the GLUT4 glucose transporter, thereby promoting the transport of glucose through the membranes and its subsequent burning. By inhibiting the synthesis of glucose in the liver, it lowers its level in the body.
Raspberry ketones - phenolic compounds, structurally close to synephrine and capsaicin, occurring mainly in raspberries, cranberries, blueberries, constituting a component of their aromatic composition. Supplied to the human body support slimming, anti-inflammatory and antiatherogenic. Increase the expression of genes of enzymes allowing lipid degradation and burning: adipocyte-specific triacylglycerol lipase (ATGL) - allows hydrolysis of triacylglycerol, hormone sensitive hormone (HSL) - responsible mainly for the breakdown of diacylglycerol and carnitine palmitoyltransferase 1B (CPT1B) - regulates the transport of long-chain fatty acids to mitochondria, allowing them to be burned. By increasing the translocation of the cytostatic-sensitive lipase-sensitive lipase into fat droplets, they intensify the norepinephrine-induced lipolysis process. They increase the rate of lipid oxidation stored in adipocytes. They enhance the breakdown of abdominal and subcutaneous fat.
Higenamine - is an alkaloid obtained mainly from the seeds of Nelumbo Nucfera - Nelumbo nucifera, in small amounts it can also be found in coffee. It demonstrates a synergistic action to NMT, causing the release of noradrenaline and adrenaline into the blood resulting in the extension of the airways and thus the increase of the body's performance. The compound acts as a stimulant, increasing energy and alertness. Higenamine reduces oxidative stress by protecting the body against free radicals.