Jarrow Formulas MSM is a dietary supplement that includes OptiMSM®, i.e. the highest quality and guaranteed purity of methylsulfonylmethane, obtained in a patented, multilayered distillation process.
The preparation is an excellent source of organic, bioavailable sulfur, which has a strong anti-inflammatory, antioxidant and analgesic effect. It is mainly used as a soothing agent for cartilage and joint problems: it reduces pain associated with degenerative joint disease, improves joint mobility, accelerates healing of injuries, and reduces swelling. The supplement can also be recommended to people complaining about the poor condition of hair, skin or nails.
Methylsulfenylmethane (dimethyl sulfone), most commonly referred to as MSM, is an oxidized form of dimethyl sulfoxide (DMSO), an organic compound that contains sulfur. It is characterized by excellent bioavailability, is safe and non-toxic (resembles water in its profile), after getting into the body it is easily absorbed and accumulates in tissues, it can also cross the blood-brain barrier.
MSM brings many health benefits - it provides the sulfur that is necessary for the proper functioning of the body; provides thiol groups that are used for glutathione synthesis; conditions the production of antibodies and enzymes; participates in the production of collagen.
MSM is a powerful antioxidant, capable of deactivating free radicals. This means that it can also reduce the intensity of oxidative stress. In addition, it is an excellent source of sulfhydryl (-SH) groups that are used in the synthesis of glutathione and endogenous antioxidant enzymes.
MSM supports cartilage and articular system. It ensures proper supply of sulfur, which is present in all major structural tissues, helps build connective tissue, is responsible for the proper condition of cartilage, tendons, ligaments and muscle fibers. Sulfur affects collagen synthesis and is part of the structure of glycosaminoglycans, which when combined with proteins form proteoglycans. Proteoglycans have gelling properties, determine the compressibility of articular cartilage, are responsible for the proper elasticity of connective tissue and as non-collagen proteins are bone building blocks.
MSM not only strengthens the locomotor system, but also alleviates discomfort that occurs within it. It has anti-inflammatory effect - limits the production of pro-inflammatory cytokines, including IL-6, IL-7 beta, IL-8, TNF-alpha, reduces the concentration of nitric oxide and E2 prostaglandins, which also participate in the inflammatory response. Effectively reduces pain, reduces swelling that accompanies inflammation, and improves range of motion in diseased joints.
Studies in patients with osteoarthritis showed that 12-week supplementation of 1125 g MSM per day was enough to reduce pain and inflammation by 33%. In addition, physical fitness improved in all people.
MSM may support the treatment of inflammatory bowel diseases. It promotes the reconstruction of the gastrointestinal lining and alleviates the symptoms associated with the so-called permeable intestine.
MSM is antiallergic. Reduces the severity of allergy symptoms such as hay fever, breathing difficulties, sneezing, watery eyes. It does not cause the drowsiness typical of many antiallergic drugs.
MSM has a significant impact on the skin, hair and nails. Increases collagen and creatine, two compounds that are responsible for skin structure, hair growth and nail condition. Thanks to this, it helps maintain smooth and elastic skin, reduces the appearance of fine wrinkles, and reduces the tendency to scarring. Strengthens hair and nails - prevents them from becoming brittle, accelerates hair growth.
MSM can support the treatment of acne, both juvenile and rosacea. In the case of juvenile acne, the antibacterial and anti-inflammatory properties of sulfur and the ability to inhibit the excessive activity of sebaceous glands are valuable. In turn, in the case of rosacea, MSM supplementation can improve skin tone and hydration, reduce the amount of unsightly facial lumps, and reduce skin sensitivity.
MSM works great in sports supplementation. First of all, it increases the strength of bones, tendons and ligaments, and thus minimizes the risk of injury. In the event of an injury, it supports therapy and reduces the time it takes to heal.
MSM reduces the amount of muscle damage that occurs as a result of protein carbonylation. It is a destructive process of protein degeneration due to the harmful effects of free radicals. Numerous studies have shown that intense physical exertion increases oxidative stress, which can be reduced by adequate MSM supply.