Freedom Formulaions Ibuta- MK677 is an oral anabolic-anti-catabolic agent based on Ibutamoren, a ghrelin mimetic.
The action of MK-677 allows to increase the concentration of growth hormone (GH, somatotropin) and insulin-like growth factor 1 (IGF-1) and to reduce the amount of cortisol in the body. Growth hormone is a peptide hormone produced by cells called somatotropes located in the glandular part. It is responsible for a number of important processes taking place in the body, including: the development of the system, the metabolism of energy substrates, the degree of intensification of anabolic and catabolic changes, the immune response and the work of the central nervous system. The regulation of periodic secretion of somatotropin is governed by somatoliberin, somatostatin and IGF-1, and among the stimuli increasing its secretion, the most frequently mentioned are: physical exercise, sleep, the supply of appropriate amino acids, hunger and the accompanying ghrelin, and the availability of some other hormones.
Ibuta-MK677 acts on the growth hormone receptors (GHS-R) and allows to increase the concentrations of: GH, IGF-1.
The ability to activate GHS-R has so far been ascribed to ghrelin. The mimicry of ghrelin in this area allowed Ibutamoren to be classified as a ghrelinomimetic. Ghrelin is a peptide hormone produced from preprogrelin, secreted mainly from the parietal cells of the stomach and fundus, which, by showing the ability to stimulate the feeling of hunger and supporting the digestive system, allows you to maintain a positive energy balance and protect the existing energy reserves of the body.
As a GHS-R ligand enabling their activation, it enhances the release of GH and IGF-1. It allows you to activate the AKT / mTOR pathway, increase the number of satellite cells, as well as reduce inflammation and reduce the activity of myostatin, thus engaging in the processes of muscle and skeletal development. Its growth properties are limited by the increased concentration of cortisol and prolactin - a hormone that limits the synthesis of luteinizing hormone (LH) and testosterone - caused by it.
MK-677, unlike ghrelin, does not increase the level of cortisol, it even lowers its amount. Additionally, it does not change the levels of prolactin and luteinizing hormone (LH). In some cases, it can lead to a decrease in total testosterone, but without interfering with the amount of free testosterone. MK-677 is an anabolic-anti-catabolic product, which, as one of the few available on the market, significantly increases the level of growth hormone without the need to inject it into the body. By increasing the amount of GH, IGF-1 and lowering cortisol, it creates ideal conditions for the development of muscle tissue and bone strengthening. By supporting the loss of excess body fat, it allows you to highlight details and present your figure.
Dosage of Freedom Formulaions Ibuta- MK677:
1-2 capsules a day.